Reyes-Lamothe Lab

McGill University

Publications

  1. Chen JJ, Moy C, Pagé V, Monnin C,El-Hajj ZW, Avizonis DZ, Reyes-Lamothe R, Tanny JC. (2024) The Rtf1/Prf1-dependent histone modification axis counteracts multi-drug resistance in fission yeast. Life Scie Alliance:7 (6): e202302494. doi: 10.26508/lsa.202302494 .

    2. The result of a collaboration with our colleagues from the Tanny lab here in McGill.

  2. d'Udekem d'Acoz O, Hue F, Ye T, Wang L, Leroux M, Rajngewerc L, Tran T, Phan K, Ramirez MS, Reisner W, Tolmasky ME, Reyes-Lamothe R (2024) Dynamics and quantitative contribution of the aminoglycoside 6'-N-acetyltransferase type Ib to amikacin resistance. mSphere: e0078923. doi: 10.1128/msphere.00789-23 .

    3. The result of an ongoing collaboration with the Tolmasky lab in Cal State Fullerton and our colleagues from the Reisner lab here in McGill.

  3. Swaffer MP, Marinov GK, Zheng H, Fuentes Valenzuela L, Tsui CY, Jones AW, Greenwood J, Kundaje A, Greenleaf WJ, Reyes-Lamothe R, Skotheim JM (2023) RNA polymerase II dynamics and mRNA stability feedback scale mRNA amounts with cell size. Cell 186: 5254. doi: 10.1016/j.cell.2023.10.012 .

    4. The result of an ongoing collaboration with the Skotheim and the Swaffer labs

  4. Liu Z, Christensen SM, Capaldi X, Hosseini SI, Zeng L, Zhang Y, Reyes-Lamothe R, Reisner, W (2023) Characterizing interaction of multiple nanocavity confined plasmids in presence of large DNA model nucleoid. Soft Matter 19:6545. doi: 10.1039/d3sm00491k.

    5. The result of an ongoing collaboration with our colleagues from the Reisner lab here in McGill.

  5. Liu Z, Capaldi X, Zeng L, Zhang Y, Reyes-Lamothe R, Reisner, W (2022) Confinement anisotropy drives polar organization of two DNA molecules interacting in a nanoscale cavity. Nat Commun. 13:4358. doi: 10.1038/s41467-022-31398-x .

    6. The result of an ongoing collaboration with our colleagues from the Reisner lab here in McGill.

  6. Bianco PR, Sale JE, Reyes-Lamothe R (2021) Editorial: Single-molecule studies of DNA-protein interactions collection 2021. Nucleic Acids Research 49:6005. doi: 10.1093/nar/gkab497 .
  7. Leroux M, Soubry N,, Reyes-Lamothe R (2021) Dynamics of Proteins and Macromolecular Machines in Escherichia coli. EcoSal Plus 9:eESP00112020. doi: 10.1128/ecosalplus.
  8. Kapadia N, El-Hajj ZW, Reyes-Lamothe R (2021) Bound2Learn: a machine learning approach for classification of DNA-bound proteins from single-molecule tracking experiments Nucleic Acid Res 49:e79. doi: 10.1093/nar/gkab186.
  9. Kapadia N, El-Hajj ZW, Zheng H, Beattie, TR, Yu A, Reyes-Lamothe R(2020)Processive Activity of Replicative DNA Polymerases in the Replisome of Live Eukaryotic Cells. Mol. Cell 80:114. doi: 10.1016/j.molcel.2020.08.014.

    10. Preview by Kellner V. & Smith D. Hold on Tight: Lagging-Strand DNA Polymerases Synthesize Multiple Okazaki Fragments without Letting Go

  10. Ladouceur AM, Parmar B, Biedzinski S, Wall J, Tope SG, Cohn D, Kim A, Soubry N, Reyes-Lamothe R, Weber SC (2020)Clusters of bacterial RNA polymerase are biomolecular condensates that assemble through liquid-liquid phase separation. PNAS 117: 18540. doi: 10.1073/pnas.2005019117 .

    11. The result of a nice collaboration with our colleagues from the Weber lab here in McGill.

  11. Wolak C, Ma HJ, Soubry N, Sandler SJ, Reyes-Lamothe R , JL Keck (2020) Interaction with single‐stranded DNA‐binding protein localizes ribonuclease HI to DNA replication forks and facilitates R‐loop removal. Mol. Microbiol. doi:10.1111/mmi.14529

    12. The result of a nice collaboration with the Keck lab at the University of Wisconsin at Madison .

  12. Kapadia N, and Reyes-Lamothe R (2019) A quest for coordination among activities at the replisome. Biochem Soc Trans, 47(4):1067-1075. doi:10.1042/BST20180402
  13. Soubry N, Wang A, and Reyes-Lamothe R (2019) Replisome activity slowdown after exposure to ultraviolet light in Escherichia coli. PNAS 116(24):11747-11753. doi: 10.1073/pnas.1819297116
  14. Reyes-Lamothe R , and Sherratt DJ (2019) The bacterial cell cycle, chromosome inheritance and cell growth. Nature Reviews Microbiology, 17(8):467-478. doi:10.1038/s41579-019-0212-7
  15. Beattie TR*, Kapadia N*, Nicolas E, Uphoff S, Wollman AJM, Leake M, and Reyes-Lamothe R (2017) Frequent exchange of the DNA polymerase during bacterial chromosome replication. eLife, doi: http://dx.doi.org/10.7554/eLife.21763

    16. Highlighted by Faculty of 1000

  16. Beattie TR & Reyes-Lamothe R (2015) Replisome’s journey through the bacterial chromosome. Frontiers in Microbiology 6: 562. doi:10.3389/fmicb.2015.00562
  17. Reyes-Lamothe R, Tran T, Meas D, Lee L, Li AM, Sherratt DJ, Tolmasky ME (2014). High-copy bacterial plasmids diffuse in the nucleoid-free space, replicate stochastically and are randomly partitioned at cell division. Nucleic Acids Res. 42, 1042-51. doi: 10.1093/nar/gkt918
  18. Uphoff, S., Reyes-Lamothe, R., Garza de Leon, F., Sherratt, D.J., Kapanidis, A.N. (2013). Single-molecule DNA repair in live bacteria. Proc Natl Acad Sci U S A 110, 8063-8068. doi: 10.1073/pnas.1301804110

    19. Highlighted by Faculty of 1000

  19. Badrinarayanan, A., Reyes-Lamothe, R., Uphoff, S., Leake, M.C., and Sherratt, D.J. (2012). In vivo architecture and action of bacterial structural maintenance of chromosome proteins. Science 338, 528-531. doi: 10.1126/science.1227126
  20. Badrinarayanan, A., Lesterlin, C., Reyes-Lamothe, R., and Sherratt, D. (2012). The Escherichia coli SMC Complex, MukBEF, Shapes Nucleoid Organization Independently of DNA Replication. J Bacteriol 194, 4669-4676. doi: 10.1128/JB.00957-12
  21. Reyes-Lamothe, R., Sherratt, D.J., and Leake, M.C. (2010). Stoichiometry and architecture of active DNA replication machinery in Escherichia coli. Science 328, 498-501. doi: 10.1126/science.1185757.

    22. Highlighted by Faculty of 1000

  22. Reyes-Lamothe, R., Possoz, C., Danilova, O., and Sherratt, D.J. (2008). Independent positioning and action of Escherichia coli replisomes in live cells. Cell 133, 90-102. doi: 10.1016/j.cell.2008.01.044.

    23. Highlighted by Faculty of 1000

    Highlighted by Nature Reviews Molecular Cell Biology

For a complete list of publications click in here

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Department of Biology | McGill University